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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee7c47341836f35539c6ffbb2a827631d8f4246a87eeb0e45a158f76953f6ca7' 
  AND token = 'z5kgOWewL75mgb74Tmk3MKiaMa0utX91F+y8F5pFugY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}