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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd438bd645a0a60463fa3773b9d6c8b99f57aef632082a9f28567e303000b9117' 
  AND token = 'vyiKcVOtZ55rpGoZydzWSSpimAPpbOnPRy/ldu+jxxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}