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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa3d078a8ad3f7b1d44705e74e7d153df49f924e41bc189cb319c28859d3ac2' 
  AND token = 'iYrorQPTxtTMUK2UoIv7m1kylDpbLJBmy5T1K+LmvsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}