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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c223bb2957eb1cebf11348cadfa8bdfc3e4f9c9416981fdb40aca8e16d4fcd5' 
  AND token = 'Prxxmfk2h1yGNNgvAuv7fE1sj+sddxKH6uZ7sXcZu4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}