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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6c99de790901c0b3e18bb3f419c88582e88a00df7b06fa776793c18495f34c' 
  AND token = 'B+n9Zk23pBbhe0FfjcqZeF5b+vpeR8YUsLdyhh8S/g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}