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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40187f97d945f8bf77811f36dbcc27fd86ffd3d54bb351d5463dac0398eb7cb' 
  AND token = 'US1lkfOMbX+5HhzNbVojl78PI7sAnwO3G6pt9jJ3Vhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}