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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491551662c40c823b73e0fd7cb69f61bf75ae85a169d3e9696c9ad97eee0b3b7' 
  AND token = 'w9JQN5MKzk3+QiKAFSQnn3PmrjR9mWXKsXnTF+rj5hc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}