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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0224b629c2c3a4c83c00897b3c367321bb65a41d09aa8f673dedb2f983ef0d14' 
  AND token = 'QdCEPD1B7AqDUb2sGBUoX7zYhbNssSVg9zfV6NeZf8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}