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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3370a100c64fa97dedcda675854a8b0cd6b55be7630224150ab16244f56e630' 
  AND token = 'XtqF7a6arZfdIUFQw4vd2SGJ8+kJ9V5VtLoMTz7Fxqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}