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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37bce7cb53098f06f6ba0efccdda4307a60f557974c5238f0e55caeb03bd0aaf' 
  AND token = 'uZkE6Ngje2WvUQO+qk0puv8uBWwN7EQpIHip1AHpqSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}