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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '730716fb917d80f46d4efcda52d7d17b91870908cc5df3ee1ab66579d0c56dc2' 
  AND token = 'frGPdozOHnAfwG/PWd/1KMa/jVDSsd1/ePoCW26fEO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}