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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de7a7ff5b8c12e46c1573ec0cb780b82dd9a6e63dacdc417006972ccd77998dc' 
  AND token = '80BWtYmmbTrYn9S/GsPBaZz8HtsftZR2zjRqwBk9JDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}