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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5bba32d74cd38cf870afb4aabe6cc85f1f568f7019774be0b1b323ed1ac8cb' 
  AND token = 'C/z553OtsM12kOZ9IXjhQu21GtW7nG154LeT98mid7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}