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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad38028d8a7ca4a5e98c321df431ecc02b51a708fd6a372449e31f9c7816926' 
  AND token = 'ncpOEW61fOiYGTIWl91cd5WNSXzMcDkzoHlW13BVVpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}