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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8194a5bc33b11d487c96ad4e590f8a71da01f6fa0a1570f25407937eb3d15351' 
  AND token = 'YdrfWg/Rao0hUjkUJF5uVjUZebjckxOGh7o2gdunoOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}