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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e401acc79ed09e7521b7998bf54edf32bf5dccc90c62c5c0b0f5f3082b442854' 
  AND token = '2bLgTDzQAZF+mVYmq2162bXMyd47HWZavaJEa8awId8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}