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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a169c7757e9fff6d3dd3fa4442bdefa44acab1df75724ae2f106b19f465bf1' 
  AND token = 'wquiYn7mtKiv9vXV88twWSBE0hcmv7SSLL9DpquIfnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}