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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e6eb811a1d7429137f4180eb79645a4da4a9d2e618de35bbd803a6e7b8da6c3' 
  AND token = '9P0E+AzT4RpAlpWNVWwsQcwvxLgRZ/obfTkTfnpwhN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}