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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3f1606fcd31909ba8321966cb9bff4b3e013ce2089fa4c96212dabfa55e632' 
  AND token = 'm0neRlzF4w3mXUROiVdroM5rf5rLcDZHuVYRPPDsYHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}