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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3325098ec4aaf830e8dbfbeb998b17e0a823926ea63df600f9b7f3023509edc3' 
  AND token = 'sw9KO62/kZDrXM5BUgB/5SybuSqG5waTtnZ7UQFaaTw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}