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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185cf8679b722b6b1829ce6723ce16400dc0152d40ce90fe0b8bd6315981bae7' 
  AND token = 'HwtyZeLnbrSuy3D3CAtJt5C3/DtAgIRZBSzBFp40QzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}