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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '821d71652a4759e00683cf192b8d1d108a58e49a1da27138593d86895811b8af' 
  AND token = '/5AHLOi2NRiIBWaDYtWBubd9/Oy4qvPtqKDrcnvLrEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}