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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cba1da52c9677e09d3a7cfb0ebb789401b20cb6921edd9781d679f852071242d' 
  AND token = 'PFQ1kCuY6S7Y+Ha5FRS5RGU9oTYhRmwrApUK4pNQVyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}