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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a751db5c755edf9344c380c734a3a73bda32058a6cbd502a671d9d2a127f7389' 
  AND token = '17ylRk4v9ybOe8dLKxEJQWJ2PsjTjz3G9uOXWrz+cBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}