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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64856b5fcc07c0624743c5c20a0b2b6929b39c41fdb8c4882fbf65f1dbd9898c' 
  AND token = 'OGBomB3VP1XkfO4ZTB7XNGVbCEEXi5yMDgFKVzADXsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}