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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd256667e4eb352ecb206db08009c62fda679b56a50961626ee765acc3b23585a' 
  AND token = 'lJjsC030j0fQDNC9rdbjIHgXgul6rA75rjFvcH0qY9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}