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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc046c8303259a3feb0e33df250249027f6de4fca694de4062eaa6d278fb0ad' 
  AND token = 'RfW66E9LVGWbrLP/V+HJcyXskd/ey9xVUXl+hmVEGa4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}