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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff15a1897ac656983034e2f038981d80489a21093273a949bef0ffe8461c2c37' 
  AND token = 'huEmd1CJMg2F+bEDtVe/w0xpLp8yMLr0RWqf3BizO2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}