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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce39c8ad26a8d8203b160ab3146de2e6325b0bc4ecee9c39701f9cbf116db706' 
  AND token = 'MA5JoNpNHQjw/ZOmBy7xzcaqQ/vfVSbnVHvldlw9QV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}