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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '763c26dd76aa345867cd3cdb2d62effc0d2da2a4ff65c30944d6f172f4640989' 
  AND token = 'KtUYCpqlLQfMBp4gjEMQr4mrKVoqRNBpyRIY8W0alzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}