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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb04cd42991c3b9086a4620eaecda3eb6f9b90c263dde3b517088567bfd0483a' 
  AND token = 'EmRN6ddOoDGMtudSQ+fWreXZGwBMAvu6ZZ5mIxac07s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}