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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d199156868375147edaecbfa331315ce70f0a0a4b386746d098ffbe4ff89721' 
  AND token = 'Ws2V+Ui9gno6lSxs+zMgI7V1QysucNdAWexG5in0rZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}