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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e36c025c3ebeff411b23d00d64e0baa46b3a3775b8b91ee5842887d3da53fe0' 
  AND token = 'oxh2cALKo4VjQhA9czQm5bRrMgEWjgw2L5NA9hPtE2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}