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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c7fc6b21b5bfcbf54a83724d4b3770159ed969e953e8d7309cf6a471909f53' 
  AND token = 'Y/nbdhUJ1vUM1qpt1a7HGAvO68gt3KiFyypUeoNUNPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}