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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ecbec1880d35d360e37d00e7b4d36329863782bc06f728798c02f33fcc841e8' 
  AND token = 'JCZRCHgqTLv21LdzaKV27hfa+fsXPAPNcTU9ZNbw9Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}