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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '022de8357b4d492c13dcf12e3d5746d34c231661156c6fc8cdf032454bfe22a3' 
  AND token = 'YrqCP14RVaVwWkxMCXvYCVVxSamjB6trLHB9X7FflSs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}