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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4012fd4b9012d7905b3e3b18d158821ff0a343a8c0fe15e32bcde890bee2fb30' 
  AND token = 'djJ3TRpBRlOTNFLQm63ac5sNW3O5l9Kkb80XdEPuJ9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}