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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4668654fcf6bedbb7fceb9e522ebfd0a291f272e264eb0a106ca60bdffb1b439' 
  AND token = 'vmId2buaptNhYvcZBKRVOPIRX1lBhM5Db9M6pdNFEYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}