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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4247578f744e25366cc8d6893d3f47c002d1f09886cb4012404ab4404a8661db' 
  AND token = 'APYuCmYdezIfzGWEmWq9shzjtqJG7oD6Mhn0r3uoVZk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}