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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b3ec8a5b16105e1413e14a75c46128a57bef32ce6cc6b11e2716553ea2e056' 
  AND token = 'nKHAh5r5EJMrv3qo8vPLQ6gDACyY4zUlVySCiAXHbUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}