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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8211ca716bbf90fed81f4d48346b3ff84b3f6e68255048d059b948b373a507de' 
  AND token = 'MWAQAMV5l3i6ByYKPDqAdcIEGN2m4RPdatlDXvJ9uwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}