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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e95f4861c699d2886374991edc5da61f0001cbd0ef97f189847643f3182f1dd4' 
  AND token = 'pwrZ1C59ck1LswyYY+mHdeRgNqhZbyBoY3lhv9wNqT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}