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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0464ae1d55566a6262418fa76951b995af4c226cefaf336ef154a15e5813f2f4' 
  AND token = 'MUXiRr5WTDlxPCEm3O1XYhYdbStdE+pF8gzPKDmZ+VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}