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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20a430a9a30d992e959f094195aa3f059d8d8648f8aa3a0a60780ac25f946b54' 
  AND token = 'DwnRsQVxaqikSq4OQW8QotxdLCPFCb0vf9rUlVgjFZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}