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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd2db96ad925ec405f0712be7eb980ac8cccb0ecf07474260e9e44dec5ce98d6' 
  AND token = 'DAwE9mzL1EMmpP/g9DY0CmzVVcssAvaMglC3Rk3XfmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}