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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a24b9b7e41228e29f804d2d96d454cadd1f38533da0c1a351fd4344dda4e5c6' 
  AND token = '4fc4SbrApu3HTM6firgVZ3d+B/Y9nNG0Pb8lQwMDiHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}