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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48d3f4e6d271603a6fbd7ac90e704ce68d4c63b082cc358356de8ca1cae3c4a5' 
  AND token = 'DtfdiDhqnlOU3fH7j9QcBh5PeSIohKsxr3M5yFhJb2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}