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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34424a3cbf80e41b95b173b78ade0de62c39147f555d44adccfda77170745f40' 
  AND token = 'ZVc/jfRYB7q449ULRwZTNaGr8O8A9jxwXW2b6+6Jryw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}