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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2453a843544cf9b05715797c30da78ee664ad9b02a01f1226897b2fbcdebc961' 
  AND token = 'YijTXGyTA5ZF+GlYsIouMxq5vAXaQlbK1e93k1kmum4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}