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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17e5256ba09057f6ffe14a89eaa64fbede6a064335ad296bbb14eb7ff0d062f2' 
  AND token = '/yfwrk+DZCXOTtymczsT9e6/ve+IHKuXwfT5ySygoAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}